Maybe the word "Top" is too strong for this list. What they really are would be best venues to find limited engagement shows. There are certainly other "Top" Venues but most of them only show the shows that they were built to show. But these are exceptions, like the Terry Fator Theater routinely has Ron White and Jay Leno but it isn't Your first guess to where they would be.
And many People do not know that if You see a show listed for Hard Rock it might be the Hard Rock Cafe on Las Vegas Blvd and not the Hard Rock on Paradise so pay close attention to that.
With more shows to choose from than any other City in the World, You might feel overwhelmed deciding on one. But if You narrow Your preference to a category, You can make Your decision much easier. If Your interest is in a Cirque du soleil show, why browse through the Comedy and Adult shows? If You want to see Britney or Mariah or JLo just browse the Concerts and headliners.
Don't like huge theaters and big crowds? Choose an afternoon Show for a much lower price.
A Dinner and Show combo is a great value and saves time to do other things that day.